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Background
I grew up in Rio de Janeiro, Brazil where I attended the
Universidade Federal do Rio de Janeiro and worked with Rui Cerqueira
on the taxonomy, morphometrics, and phenotypic evolution of oppossums. Upon graduation, I
entered the Master program
in genetics at the same university to work with Hector
N. Seuanez at the National Cancer Institute, Brazil, on the molecular evolution and phylogenetics
of primates and the phylogenetic footprinting of the developmental gene Sonic Hedgehog. I came to the Hartl
Lab as a student in September 2001 and defended my PhD dissertation last January (2007, Harvard University)
focusing on the evolution of genomic expression and working with both experimental and computational tools.
Research interests
I use principles of evolutionary theory and populations genetics to understand genomic expression
and diversity. In pursuing this goal I am curious about _anything_ underlying variation in the expression of genes
and whole genomes, from SNPs to methylation patterns to histone distribution to "heterochromatin effects" to alternative
splicing to chromosome organization in the nucleus, and so on. Overall, I pursue an integrative line of research that
incorporates genomic approaches and classical molecular evolutionary genetics, and attempts to use a variety of
data sources towards addressing synthetic questions.
Publications
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Lemos B. 2007. Regulatory evolution and the correlates of
mammalian diversification: punches from the opossum genome. Genome Biology in press
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Lemos B, Landry CR, Fontanillas P, Renn S, Kulatinhal R, Brown KM, Hartl DL. 2007. Evolution of Genomic Expression.
In Evolutionary Genomics and Proteomics, edited by Pagel M & Pomiankowski A. Sinauer Press, Massachussets. in press
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Landry* CR, Lemos* B, Rifkin SA, Dickinson WJ, Hartl DL. 2007.
Genetic properties influencing the evolvability of gene expression. Science 317: 118-121.
*these authors contributed equally
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Bonvicino CR, Lemos B, Weksler M. 2005.
Small mammals of Chapada dos Veadeiros National Park (Cerrado of Central Brazil).
Ecologic, karyologic and taxonomic considerations. Brazilian Journal of Biology 65(3): 395-406.
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Lemos B, Bettencourt BR, Meiklejohn CD, Hartl DL. 2005. Evolution of proteins
and gene expression levels are coupled in Drosophila and are independently associated with
mRNA abundance, protein length, and number of protein-protein interactions. Molecular Biology and Evolution 22(5): 1345-1354.
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David JR, Araripe LO, Chakir M, Legout H, Lemos B, Rohmer C,
Joly D, Moreteau B. 2005. Male sterility at extreme temperatures: a significant but
neglected phenomenon for understanding Drosophila climatic adaptations.
Journal of Evolutionary Biology 18(4): 838-846.
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Lemos B, Meiklejohn CD, Caceres M, Hartl DL. 2005.
Rates of divergence in gene expression profiles of primates, mice, and flies:
stabilizing selection and variability among functional categories.
Evolution 59(1): 126-137.
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Lemos B, Meiklejohn CD, Hartl DL. 2004.
Regulatory evolution across the protein interaction network.
Nature Genetics 36(10): 1059-1060.
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Lemos B, Yunes JA, Vargas F, Moreira MAM, Cardoso, AA, Seuánez HN. 2004.
Phylogenetic footprinting reveals extensive conservation of Sonic Hedgehog (SHH) regulatory elements.
Genomics 84(3): 512-524.
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Bonvicino CR, Penna-Firme V, Nascimento FF, Lemos B, Stanyon R, Seuánez HN. 2003.
The lowest diploid number (2n = 16) yet found in any primate: Callicebus lugens (Humboldt, 1811).
Folia Primatologica 74 (3): 141-149.
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Lemos B and Cerqueira R. 2002. Morphological differentiation in the white-eared
opossum group (Didelphidae, Didelphis). Journal of Mammalogy 83(2): 354-369.
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Seuanez HN, Lima CR, Lemos B, Bonvicino CR, Moreira MAM, Canavez FC.
2001. Gene assignment in Ateles paniscus chamek (Platyrrhini, Primates). Allocation
of 18 markers of human syntenic groups 1, 2, 7, 14, 15, 17 and 22. Chromosome Research
9(8): 631-639.
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Lemos B, Marroig G, Cerqueira R. 2001. Evolutionary rates and stabilizing
selection in large-bodied opossum skulls (Didelphimorphia : Didelphidae). Journal of
Zoology 255: 181-189.
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de Moraes DA, Lemos B, Cerqueira R. 2001. Supernumerary molars in
neotropical opossums (Didelphimorphia, Didelphidae). Mammalian Biology 66 (4): 193-203.
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Bonvicino CR, Lemos B, Seuanez HN. 2001. Molecular phylogenetics
of howler monkeys (Alouatta, Platyrrhini) - A comparison with karyotypic data.
Chromosoma 110 (3): 241-246.
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Lemos B, Weksler M, Bonvicino CR. 2000. The taxonomic status of
Monodelphis umbristriata (Didelphimorphia : Didelphidae). Mammalia 64 (3): 329-337.
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Cerqueira R, Lemos B. 2000. Morphometric differentiation between
Neotropical black-eared opossums, Didelphis marsupialis and D. aurita
(Didelphimorphia, Didelphidae). Mammalia 64 (3): 319-327.
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Lemos B, Canavez F, Moreira MAM. 1999. Mitochondrial DNA-like sequences
in the nuclear genome of the opossum genus Didelphis (Marsupialia : Didelphidae).
Journal of Heredity 90(5): 543-547.
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Hobbies
I enjoy reading, going for long walks, killing time at the beach, playing tennis, surfing, doing outside sports.
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