Active Research

Evolutionary genomics
of Drosophila

Genetic diversity of P. falciparum

Evolution of hybrid incompatibilities

Evolution of gene expression

Natural selection and protein evolution

 
Past Research

Evolution of novel gene functions

Bioinformatics

Selective sweep

C-value paradox

Transposable element mariner

Structure and sequence of the Drosophila genome

Genome structure and evolution in D. virilis

Cosuppression of transposable elements

Molecular evolution in enteric bacteria

Gregor Mendel

Cosuppression of transposable elements and hybrid dysgenesis

We studied a system of hybrid dysgenesis in Drosophila virilis in which at least four unrelated transposable elements are all mobilized following a dysgenic cross. The data are largely consistent with the loss of cosuppression of different families of transposable elements. These families include Ulysses and Telemac (both LTR-containing retrotransposon), Helena (a non-LTR retrotransposon), Paris (a cut-and-paste DNA transposon) and Penelope (a transposable element of uncertain functional affiliation).

 
  Vieira, J., C. P. Vieira, D. L. Hartl, and E. R. Lozovskaya. 1998 Factors contributing to the hybrid dysgenesis syndrome in Drosophila virilis. Genet. Res. 71: 109-117.  
 
PDF Petrov, D. A., J. L. Schutzman, D. L. Hartl and E. R. Lozovskaya, 1995 Diverse transposable elements are mobilized in hybrid dysgenesis in Drosophila virilis. Proc. Natl. Acad. Sci. USA 92: 8050-8054