Christopher Marx
Assistant Professor of Organismic & Evolutionary Biology
Phone: 617-496-8103
E-mail:
Office: 3083 BioLabs, 16 Divinity Ave
Lab Website: http://www.oeb.harvard.edu/faculty/marx/
Experimental evolution of microbes to address broad evolutionary and ecological questions and explore the systems-level function and optimization of complex biological networks.
Recent Publications
Chain, P. S. G., V. J. Denef, K. Konstantinidis, L. M Vergez, L. Agulló, V. Latorre Reyes, L. Hauser, M. Córdova, L. Gómez, M. González, M. Land, V. Lao, F. Larimer, J. J. LiPuma, E. Mahenthiralingam, S. A. Malfatti, C. J. Marx , J. J. Parnell, A. Ramette, P. Richardson, M. Seeger, D. Smith, T. Spilker, W. J. Sul, T. V. Tsoi, L. E. Ulrich, I. B. Zhulin, and J. M. Tiedje. 2006. Burkholderia xenovorans LB400 harbors a multi-replicon, 9.73 Mbp genome shaped for versatility. Proc. Natl. Acad. Sci. USA 103:15280-15287
Kalyuzhnaya, M. G., N. Korotkova, G. Crowther, C. J. Marx , M. E. Lidstrom, and L. Chistoserdova. 2005. Analysis of gene islands involved in methanopterin-linked C 1 transfer reactions, deduction of novel C 1 transfer genes, and new insights into the evolution of "archaeal" genes in bacteria. J. Bacteriol. 187:4607-4614
Marx, C. J., S. J. Van Dien, and M. E. Lidstrom. 2005. Flux analysis uncovers key role of functional redundancy in formaldehyde pathways. PLoS Biol. 3:e16 [Highlighted in Nature Reviews Microbiology 3:103]
Marx, C. J., J. A. Miller, L. Chistoserdova, and M. E. Lidstrom. 2004. Multiple formaldehyde oxidation pathways in Burkholderia fungorum LB400. J. Bacteriol. 186:2173-2178
Chistoserdova, L., C. Jenkins, M. G. Kalyuzhnaya, C. J. Marx, A. Lapidus, J. T. Staley, and M.E. Lidstrom. 2004. The enigmatic Planctomyces may hold a key to the origins of methanogenesis and methylotrophy. Mol. Biol. Evol. 21:1234-1241
Courses Taught
OEB 192. Microbial Evolution
OEB 279. Topics in Microbial Metabolic Systems
OEB 365. Evolution of Microbes
