John Wakeley

Professor
Department of Organismic & Evolutionary Biology
telephone: (617) 495-1564
fax: (617) 384-5874
email: wakeley@fas.harvard.edu



Research

Fundamentally, my research is about extracting information from population samples of DNA sequences. I use mathematical models to understand how a variety of current and historical factors conspire to produce the patterns of variation which are readily observable among individuals within species. I use both analytical and computational techniques to make inferences about these factors from patterns of genetic variation.

This field is called Theoretical Population Genetics, and my own research has mainly been in three areas: (1) the study of finely-subdivided populations, often called metapopulations, where much of my work has been on the many-demes model, (2) the study of human history, where the focus has been on inferring historical events in the context of our demographically-complex population, and (3) the study of diverging populations or closely-related species, which has resulted in a series of methods for disentangling the various historical factors which shape genetic variation.

Follow this publications link for references and articles to download.

This work has been supported by grants from the National Science Foundation. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.


Teaching

I teach Life Sciences 1b, OEB 152: Population Genetics, OEB 252: Coalescent Theory, and OEB 253r: Seminar in Evolutionary Genetics. You can read descriptions of them here.

I wrote a textbook for Coalescent Theory. You can find it at Amazon.com or at Roberts & Company Publishers.


Other

Back to the lab.

If you like Mark Rothko paintings, this is "Orange and Yellow" from 1956. This scan is by Mark Harden. Go to his site for more and, especially, to read about copyright laws and the fair use of artistic images.