#  2024 Prather Lecture Series: Molly F. Przeworski 

 



####  calendar\_today Date and Time 

 **May 3, 2024** 

 12:00PM - 12:00PM EDT 

####  pin\_drop Location 

 **Bio Labs Lecture Hall 1080, 16 Divinity Avenue**  



 

 



 

   ![Molly Przeworski_Prather 2024](/sites/g/files/omnuum6811/files/styles/hwp_1_1__360x360_scale/public/oeb/files/molly_f_przeworski_web.jpeg?itok=DpEpgffG) 

 

[Molly F. Przeworski](https://systemsbiology.columbia.edu/faculty/molly-przeworski/pmg-people)  
Alan H. Kempner Professor of Biological Sciences and Systems Biology  
Columbia University

[*Why do human germline mutation rates depend on sex and age?*](/prather-lecture-series)

**Abstract:** Germline mutation is the source of all heritable differences and therefore of fundamental importance. In mammals, it has long been appreciated that mutation rates are higher in fathers, particularly older fathers. The textbook view has long been that these patterns reflect replication errors that accrue during spermatogenesis. Dr. Przeworski will present multiple lines of evidence that call this view into question. She will argue instead that current data are best explained by a much larger role of DNA damage in the genesis of germline mutations than previously appreciated, and draw implications for why mutation rates depend on sex and age and how they evolve over time.

Co-sponsored by The Departments of Molecular and Cellular Biology and Organismic and Evolutionary Biology



 

 



 

 See also:- [ Prather Lecture Series ](/event-type/prather-lecture-series)
 
 

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