#  2025 Prather Lecture Series: Feng Zhang 

 



####  calendar\_today Date and Time 

 **April 4, 2025** 

 12:00PM - 01:00PM EDT 

####  pin\_drop Location 

 **Bio Labs Lecture Hall 1080, 16 Divinity Ave**  



 

 



 

   ![Feng Zhang- 2025 Prather Lecturer](/sites/g/files/omnuum6811/files/styles/hwp_1_1__360x360_scale/public/2025-03/Feng%20Zhang%20crop.jpeg?itok=4OgWKdMn) 

 

[Dr. Feng Zhang](https://www.zlab.bio/)   
Investigator, Howard Hughes Medical Institute  
Core Member, Broad Institute of MIT and Harvard  
Investigator, McGovern Institute for Brain Research, MIT  
James and Patricia Poitras Professor in Neuroscience, MIT  
Departments of Brain and Cognitive Sciences and Biological Engineering, MIT

[*Engineering Physiology*](https://www.oeb.harvard.edu/prather-lecture-series)

**Abstract:** Cell state and identity are largely defined by combinations of transcription factors, and a number of studies have shown that exogenous expression of certain transcription factors can alter cell state and identity. The ability to modulate cell state would unlock new opportunities for engineering physiology, enabling cell replacement therapies and restoration of cellular homeostasis in disease and age. In this lecture, Zhang will describe his work mapping the effects of transcription factor expression on stem cell fate using a library of human transcription factor ORFs. In addition, he will describe a related approach to identify factors lost during immune-aging and his efforts to transiently restore these factors.

Co-sponsored by The Departments of Molecular and Cellular Biology and Organismic and Evolutionary Biology



 

 



 

 See also:- [ Prather Lecture Series ](/event-type/prather-lecture-series)
 
 

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