#  OEB Seminar Series: Kara McKinley 

 



####  calendar\_today Date and Time 

 **February 8, 2024** 

 03:30PM - 03:30PM EST 

####  pin\_drop Location 

 **Northwest Building B101, 52 Oxford St.**  



 

 



 

   ![Kara McKinley](/sites/g/files/omnuum6811/files/styles/hwp_1_1__360x360_scale/public/oeb/files/kara_mckinley.jpg?itok=sgWTOGG6) 

 

[Kara McKinley](/mckinleylab.org)  
Assistant Professor of Stem Cell and Regenerative Biology  
Harvard Stem Cell Institute  
Harvard University *Regeneration in the uterus*

 **Abstract:** The lining of the uterus (endometrium) is a tremendously powerful system to understand regeneration. During menstruation, the endometrium sheds millimeters of complex tissue alongside substantial bleeding. The endometrium is destroyed and rebuilt approximately 400 times over the reproductive lifespan, rendering it an exceptional resource to uncover mechanisms of regeneration in a human context. Moreover, understanding this remarkable tissue is critical to address the longstanding unmet needs of hundreds of millions of patients around the world with infertility, endometriosis, adenomyosis, endometrial cancers, and abnormal uterine bleeding. Even though approximately 1.4 billion people worldwide are menstruating, our molecular understanding of this recurring life event is sparse. This circumstance arises, in part, because menstruation is an extremely rare trait among mammals. Most mammals, including common laboratory animals such as mice and rats, do not menstruate. I will present our ongoing work to understand how menstruation evolved with the goal of generating a transgenic mouse that menstruates.

 **Host:** Professor Mansi Srivastava



 

 



 

 See also:- [ OEB Seminars ](/event-type/oeb-seminars)
 
 

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